Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein Stability.

Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein Stability.

G9a is a lysine methyltransferase (KMTase) for histone H3 lysine 9 that plays critical roles in a number of biological processes. Emerging evidence suggests that aberrant expression of G9a contributes to tumor metastasis and maintenance of a malignant phenotype in cancer by inducing epigenetic silen...

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Bibliographic Details
Main Authors: Jae-Young Lee, Se-Hwan Lee, Sun-Hee Heo, Kwang-Soo Kim, Changhoon Kim, Dae-Kwan Kim, Jeong-Jae Ko, Kyung-Soon Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619656?pdf=render

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http://europepmc.org/articles/PMC4619656?pdf=render

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