Acute tuft cell ablation in mice induces malabsorption and alterations in secretory and immune cell lineages in the small intestine

Abstract Intestinal tuft cells have recently been the focus of many studies due to their function in chemosensation and type 2 immunity in human gastrointestinal diseases. This study investigated the impact of acute tuft cell loss on intestinal physiological function. Tuft cell deletion was induced...

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Bibliographic Details
Main Authors: Michael Momoh, Francisca Adeniran, Cynthia Ramos, Kathleen E. DelGiorno, Hiroshi Seno, Joseph T. Roland, Izumi Kaji
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.70264