Early mechanisms of neutrophil activation and transmigration in acute lung injury

Early mechanisms of neutrophil activation and transmigration in acute lung injury

Introduction:Neutrophil transmigration is multifactorial and primarily driven by selectins and β2-integrins (CD11b/CD18), whose expression are dependent on the underlying stimulus. Ventilator-induced lung injury (VILI) results in a predominantly CD18-independent mechanism of neutrophil recruitment,...

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Bibliographic Details
Main Authors: L. A. Cagle, A. L. Linderholm, L. M. Franzi, J. A. Last, S. I. Simon, N. J. Kenyon, R. W. Harper
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Physiology
Subjects:
neutrophil migration
dual oxidase
neutrophil activation
acute lung injury
mouse model
CD18
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1059686/full

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https://www.frontiersin.org/articles/10.3389/fphys.2022.1059686/full

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