Synthesis of 11, 12-2H2- and 11, 12-3H2-labeled chenodeoxycholic and lithocholic acids

Deuterium- and tritium-labeled chenodeoxycholic acid and lithocholic were prepared by catalytic reduction of their respective Δ11 derivatives. Structures of the intermediates and their isotopic purity were verified by chemical ionization and electron impact mass spectrometry and by nuclear magnetic...

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Bibliographic Details
Main Authors: A E Cowen, A F Hofmann, D L Hachey, P J Thomas, D T Belobaba, P D Klein, L Tökes
Format: Article
Language:English
Published: Elsevier 1976-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520369790