SRC plays a specific role in the cross-talk between apoptosis and autophagy via phosphorylation of a novel regulatory site on AMPK

SRC plays a specific role in the cross-talk between apoptosis and autophagy via phosphorylation of a novel regulatory site on AMPK

Cell detachment from the extracellular matrix (ECM) typically promotes cell death via a form of apoptosis known as anoikis. However, in tumor cells, detachment can also induce cell survival, utilizing a process known as macroautophagy/autophagy, which involves degradation and removal of apoptotic pr...

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Bibliographic Details
Main Authors: Ming Zhao, Darren Finlay, Robert Liddington, Kristiina Vuori
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Autophagy Reports
Subjects:
ampk
apoptosis
autophagy
cell attachment
cell detachment
phosphorylation
ptk2/fak
src
Online Access:http://dx.doi.org/10.1080/27694127.2022.2047266

Internet

http://dx.doi.org/10.1080/27694127.2022.2047266

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