Role of ammonia in NAFLD: An unusual suspectKey points

Role of ammonia in NAFLD: An unusual suspectKey points

Summary: Mechanistically, the symptomatology and disease progression of non-alcoholic fatty liver disease (NAFLD) remain poorly understood, which makes therapeutic progress difficult. In this review, we focus on the potential importance of decreased urea cycle activity as a pathogenic mechanism. Ure...

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Bibliographic Details
Main Authors: Karen Louise Thomsen, Peter Lykke Eriksen, Annarein JC. Kerbert, Francesco De Chiara, Rajiv Jalan, Hendrik Vilstrup
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:JHEP Reports
Subjects:
Ammonia
Cellular senescence
Epigenetics
Glutamine metabolism
Non-alcoholic fatty liver disease
Urea synthesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923001118

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http://www.sciencedirect.com/science/article/pii/S2589555923001118

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