ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest

ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest

ZFP36L2 promotes the destruction of AU-rich element-containing transcripts, while its regulation and functional significance in cell cycle control are scarcely identified. We show that ZFP36L2 is a cell cycle-regulated CCCH protein, the abundance of which is regulated post-translationally at the res...

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Bibliographic Details
Main Authors: Aya Noguchi, Shungo Adachi, Naoto Yokota, Tomohisa Hatta, Tohru Natsume, Hiroyuki Kawahara
Format: Article
Language:English
Published: The Company of Biologists 2018-03-01
Series:Biology Open
Subjects:
Cell cycle
DNA damage response
Ubiquitin
Protein degradation
CCCH-zinc finger domain
RNA-binding protein
Online Access:http://bio.biologists.org/content/7/3/bio031575

Internet

http://bio.biologists.org/content/7/3/bio031575

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