Comparative evaluation of full-length isoform quantification from RNA-Seq

Comparative evaluation of full-length isoform quantification from RNA-Seq

Abstract Background Full-length isoform quantification from RNA-Seq is a key goal in transcriptomics analyses and has been an area of active development since the beginning. The fundamental difficulty stems from the fact that RNA transcripts are long, while RNA-Seq reads are short. Results Here we u...

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Bibliographic Details
Main Authors: Dimitra Sarantopoulou, Thomas G. Brooks, Soumyashant Nayak, Antonijo Mrčela, Nicholas F. Lahens, Gregory R. Grant
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Bioinformatics
Subjects:
Benchmarking
Isoform quantification
Simulated data
Pseudo-alignment
RNA-seq
Short reads
Online Access:https://doi.org/10.1186/s12859-021-04198-1

Internet

https://doi.org/10.1186/s12859-021-04198-1

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