Novel Hydroxytyrosol-Donepezil Hybrids as Potential Antioxidant and Neuroprotective Agents

Novel Hydroxytyrosol-Donepezil Hybrids as Potential Antioxidant and Neuroprotective Agents

It is well-accepted that the endogenous antioxidant protection system progressively decays in elderly people, and that the oxidative stress contributes to different neurodegenerative disorders such as Alzheimer’s Diseases (AD). The lower incidence of AD in countries which feature the Mediterranean D...

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Bibliographic Details
Main Authors: Paola Costanzo, Manuela Oliverio, Jessica Maiuolo, Sonia Bonacci, Giuseppina De Luca, Mariorosario Masullo, Rosaria Arcone, Antonio Procopio
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Chemistry
Subjects:
antioxidant
bio-phenols
neurodegeneration
bio-metal chelator
reactive oxygen species
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.741444/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.741444/full

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