Transient Receptor Potential Ankyrin 1 (TRPA1) Is Involved in Upregulating Interleukin-6 Expression in Osteoarthritic Chondrocyte Models

Transient Receptor Potential Ankyrin 1 (TRPA1) Is Involved in Upregulating Interleukin-6 Expression in Osteoarthritic Chondrocyte Models

Transient receptor potential ankyrin 1 (TRPA1) is a membrane-bound ion channel found in neurons, where it mediates nociception and neurogenic inflammation. Recently, we have discovered that TRPA1 is also expressed in human osteoarthritic (OA) chondrocytes and downregulated by the anti-inflammatory d...

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Bibliographic Details
Main Authors: Elina Nummenmaa, Mari Hämäläinen, Antti Pemmari, Lauri J. Moilanen, Lauri Tuure, Riina M. Nieminen, Teemu Moilanen, Katriina Vuolteenaho, Eeva Moilanen
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
osteoarthritis
chondrocyte
TRPA1
IL-6
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/1/87

Internet

https://www.mdpi.com/1422-0067/22/1/87

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