Haploinsufficiency of the sex-determining genes at MATα restricts genome expansion in Saccharomyces cerevisiae

Summary: In Saccharomyces cerevisiae, mating type of haploid cells is determined by the presence or absence of the MATα idiotype containing MATα1 and MATα2, which encode the transcription factors. These proteins are characterized by rapid turnover, but the physiological relevance of this property re...

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Bibliographic Details
Main Authors: Kazumasa Oya, Akira Matsuura
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010550