Association between genetic polymorphisms of CYP2C9 and VKORC1 and safety and efficacy of warfarin: Results of a 5 years audit

Association between genetic polymorphisms of CYP2C9 and VKORC1 and safety and efficacy of warfarin: Results of a 5 years audit

Objective: Genetic polymorphisms of CYP2C9 and VKORC1 play major role in pharmacokinetics and pharmacodynamics of warfarin, respectively. Purpose of our study was to assess the utility of pretesting patients for the above mutations in predicting tendency for bleeding and achieving target INR. Method...

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Main Authors: Mansij Biswas, Shital R. Bendkhale, Siddharth P. Deshpande, Saket J. Thaker, Dwarkanath V. Kulkarni, Shobna J. Bhatia, Anjali G. Rajadhyaksha, Nithya J. Gogtay, Urmila M. Thatte
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Indian Heart Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S0019483217308039

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http://www.sciencedirect.com/science/article/pii/S0019483217308039

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