Novel Morphological Profiling Assay Connects ex Vivo Endothelial Cell Responses to Disease Severity in Liver Cirrhosis

Novel Morphological Profiling Assay Connects ex Vivo Endothelial Cell Responses to Disease Severity in Liver Cirrhosis

Background and Aims: Endothelial cell (EC) dysfunction in response to circulating plasma factors is a known causal factor in many systemic diseases. However, no appropriate assay is available to investigate this causality ex vivo. In liver cirrhosis, systemic inflammation is identified as central me...

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Bibliographic Details
Main Authors: Rudmer J. Postma, Annelotte G.C. Broekhoven, Hein W. Verspaget, Hetty de Boer, Thomas Hankemeier, Minneke J. Coenraad, Vincent van Duinen, Anton Jan van Zonneveld
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Gastro Hep Advances
Subjects:
Endothelial Cell Dysfunction
Liver Cirrhosis
Morphological Profiling
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572323001656

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http://www.sciencedirect.com/science/article/pii/S2772572323001656

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