New Insights on the miRNA Role in Diabetic Tendinopathy: Adipose-Derived Mesenchymal Stem Cell Conditioned Medium as a Potential Innovative Epigenetic-Based Therapy for Tendon Healing

New Insights on the miRNA Role in Diabetic Tendinopathy: Adipose-Derived Mesenchymal Stem Cell Conditioned Medium as a Potential Innovative Epigenetic-Based Therapy for Tendon Healing

Background: Adipose-derived mesenchymal stem cell conditioned medium (ASC-CM) improved the viability and wound closure of human tenocytes (HTCN) exposed to high glucose (HG) by activating the transforming growth factor beta 1 (TGF-β1) pathway. Objectives: Since ASC-CM can also modulate microRNAs (mi...

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Bibliographic Details
Main Authors: Marina Russo, Caterina Claudia Lepre, Gianluca Conza, Nicoletta Tangredi, Giovanbattista D’Amico, Adriano Braile, Antimo Moretti, Umberto Tarantino, Francesca Gimigliano, Michele D’Amico, Maria Consiglia Trotta, Giuseppe Toro
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomolecules
Subjects:
diabetic tendinopathy
microRNAs
adipose-derived mesenchymal stem cell
conditioned medium
Online Access:https://www.mdpi.com/2218-273X/15/2/264

Internet

https://www.mdpi.com/2218-273X/15/2/264

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