Inhibition of complex I-III activity of brain mitochondria after intracerebroventricular administration of streptozotocin in rats is possibly related to loss of body weight

Inhibition of complex I-III activity of brain mitochondria after intracerebroventricular administration of streptozotocin in rats is possibly related to loss of body weight

The effects of streptozotocin (STZ) on the brain after intracerebroventricular (ICV) administration in rodents have been suggested to mimic the pathogenesis of sporadic Alzheimer's disease (AD). Oxidative damage, decreased glucose utilization, mitochondrial bioenergetic changes, neuroinflammati...

Full description

Bibliographic Details
Main Authors: Jit Poddar, Sukhpal Singh, Pardeep Kumar, Sharadendu Bali, Sumeet Gupta, Sasanka Chakrabarti
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Heliyon
Subjects:
Alzheimer's disease
Cognitive deficit
Mitochondria
Oxidative damage
Streptozotocin
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020313347

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020313347

Similar Items