Expression profiles analysis identifies specific interferon-stimulated signatures as potential diagnostic and predictive indicators of JAK2V617F+ myelofibrosis

Expression profiles analysis identifies specific interferon-stimulated signatures as potential diagnostic and predictive indicators of JAK2V617F+ myelofibrosis

Objective: This study aimed to identify specific dysregulated genes with potential diagnostic and predictive values for JAK2V617F+ myelofibrosis.Methods: Two gene expression datasets of CD34+ hematopoietic stem and progenitor cells (HSPCs) from patients with JAK2V617F+ myeloproliferative neoplasm (M...

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Bibliographic Details
Main Authors: Yanhong Zhao, Di Wang, Yipeng Liang, Changlu Xu, Lihong Shi, Jingyuan Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
Myelofibrosis
JAK2V617F
MPN
Interferon (IFN)
Prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.927018/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.927018/full

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