MYR1-Dependent Effectors Are the Major Drivers of a Host Cell’s Early Response to <italic toggle="yes">Toxoplasma</italic>, Including Counteracting MYR1-Independent Effects

MYR1-Dependent Effectors Are the Major Drivers of a Host Cell’s Early Response to <italic toggle="yes">Toxoplasma</italic>, Including Counteracting MYR1-Independent Effects

ABSTRACT The obligate intracellular parasite Toxoplasma gondii controls its host cell from within the parasitophorous vacuole (PV) by using a number of diverse effector proteins, a subset of which require the aspartyl protease 5 enzyme (ASP5) and/or the recently discovered MYR1 protein to cross the...

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Bibliographic Details
Main Authors: Adit Naor, Michael W. Panas, Nicole Marino, Michael J. Coffey, Christopher J. Tonkin, John C. Boothroyd
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
Toxoplasma gondii
effector functions
host response
host-parasite relationship
Online Access:https://journals.asm.org/doi/10.1128/mBio.02401-17

Internet

https://journals.asm.org/doi/10.1128/mBio.02401-17

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