Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes

Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes

The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) that are stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-nucleated F-actin ‘shell’ in starfis...

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Bibliographic Details
Main Authors: Natalia Wesolowska, Ivan Avilov, Pedro Machado, Celina Geiss, Hiroshi Kondo, Masashi Mori, Peter Lenart
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
oocyte meiosis
nuclear envelope
starfish oocytes
electron microscopy
superresolution
Online Access:https://elifesciences.org/articles/49774

Internet

https://elifesciences.org/articles/49774

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