Radotinib inhibits multiple myeloma cell proliferation via suppression of STAT3 signaling.

Multiple myeloma (MM) is a hematological cancer causing from accumulated abnormal plasma cells. STAT3 overexpression in MM appears to be mediated by a variety of factors, and it may be associated with an adverse prognosis and play a role in microenvironment-dependent treatment resistance. Unfortunat...

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Bibliographic Details
Main Authors: Sook-Kyoung Heo, Eui-Kyu Noh, Hye Jin Seo, Yoo Jin Lee, SuJin Koh, Young Joo Min, Yunsuk Choi, Jae-Cheol Jo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0265958