CHANGES IN MUCOSA-ASSOCIATED INVARIANT T CELLS (MAIT), ASSOCIATED CYTOKINES, AND MR-1+ CELL NUMBER AND PHENOTYPE IN THE PERIPHERAL BLOOD OF PEDIATRIC ITP PATIENTS WITH AND WITHOUT ELTROMBOPAG THERAPY

Objective: Immune thrombocytopenia (ITP) is an autoimmune disease characterized by thrombocytopenia caused by the formation of antibodies against platelets. Mucosa-associated invariant T cells (MAIT), a subset of unconventional T cells present in the blood and mucosa, are activated in an MR-1-mediat...

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Main Authors: Ahmet Eken, Metin Çil, Zehra Busra Azizoglu, Ramazan Üzen, Nazly Najat ASAAD, Sahin CALIK, Koray DORTERLER, Enes Mehmet Turkoglu, Yunus Emre DOĞAN, Ebru Yılmaz, Alper Ozcan, Musa Karakükçü, Goksel Leblebisatan, Ekrem Ünal
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137923002067