Particle size of latex beads dictates IL-1β production mechanism.

Macrophages (Mϕ) are well documented to produce IL-1β through various signaling pathways in response to small particles such as silica, asbestos and urea crystals, in the presence of lipopolysaccharide (LPS). However, it has not been clear to what extent particle size affects the response. To invest...

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Bibliographic Details
Main Authors: Takumi Adachi, Kazuhiko Takahara, Jun Taneo, Yasuo Uchiyama, Kayo Inaba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3711474?pdf=render