A Four-Week High-Fat Diet Induces Anxiolytic-like Behaviors through Mature BDNF in the mPFC of Mice

The effect of a high-fat diet (HFD) on mood is a widely debated topic, with the underlying mechanisms being poorly understood. This study explores the anxiolytic effects of a four-week HFD in C57BL/6 mice. Five-week-old mice were exposed to either an HFD (60% calories from fat) or standard chow diet...

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Bibliographic Details
Main Authors: Huixian Huang, Jia Huang, Wensi Lu, Yanjun Huang, Ran Luo, Luqman Bathalian, Ming Chen, Xuemin Wang
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/14/4/389