Genome-Wide DNA Methylation Changes Associated With High-Altitude Acclimatization During an Everest Base Camp Trek

Genome-Wide DNA Methylation Changes Associated With High-Altitude Acclimatization During an Everest Base Camp Trek

The individual physiological response to high-altitude hypoxia involves both genetic and non-genetic factors, including epigenetic modifications. Epigenetic changes in hypoxia factor pathway (HIF) genes are associated with high-altitude acclimatization. However, genome-wide epigenetic changes that a...

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Bibliografski detalji
Glavni autori: Ainash Childebayeva, Taylor Harman, Julien Weinstein, Trevor Day, Tom D. Brutsaert, Abigail W. Bigham
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2021-06-01
Serija:Frontiers in Physiology
Teme:
epigenetics (DNA methylation)
genome-wide DNA methylation analysis
high altitude acclimatization
HIF pathway
hypoxia
Online pristup:https://www.frontiersin.org/articles/10.3389/fphys.2021.660906/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.660906/full

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