Combined effect of DBM, PRP, and bone marrow fluid on bone union in a rat posterolateral fusion model

Combined effect of DBM, PRP, and bone marrow fluid on bone union in a rat posterolateral fusion model

Abstract Platelet-rich plasma (PRP) promotes bone union through osteoinduction. We investigated whether adding demineralized bone matrix (DBM), derived naturally from biomaterial and with various growth factors, for osteoconductivity and bone marrow fluid for osteogenesis results in different bone u...

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Bibliographic Details
Main Authors: Takuma Otagiri, Yasuhiro Shiga, Takashi Hozumi, Yusuke Matsuura, Ikuko Tajiri, Naoya Takayama, Maria Alejandra, Yuki Shiko, Sumihisa Orita, Kazuhide Inage, Yawara Eguchi, Takane Suzuki, Miyako Suzuki-Narita, Michiaki Mukai, Tomohito Mukaihata, Ryuto Tsuchiya, Soichiro Tokeshi, Kohei Okuyama, Takahito Arai, Noriyasu Toshi, Takeo Furuya, Satoshi Maki, Yasuchika Aoki, Seiji Ohtori
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41844-5

Internet

https://doi.org/10.1038/s41598-023-41844-5

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