Paired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism across transcription factors

Paired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism across transcription factors

Abstract Cooperativity and antagonism between transcription factors (TFs) can drastically modify their binding to regulatory DNA elements. While mapping these relationships between TFs is important for understanding their context-specific functions, existing approaches either rely on DNA binding mot...

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Bibliographic Details
Main Authors: Anna Berenson, Ryan Lane, Luis F. Soto-Ugaldi, Mahir Patel, Cosmin Ciausu, Zhaorong Li, Yilin Chen, Sakshi Shah, Clarissa Santoso, Xing Liu, Kerstin Spirohn, Tong Hao, David E. Hill, Marc Vidal, Juan I. Fuxman Bass
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42445-6

Internet

https://doi.org/10.1038/s41467-023-42445-6

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