The Strategies for Treating “Alzheimer’s Disease”: Insulin Signaling May Be a Feasible Target

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by senile plaques formed by amyloid-beta (Aβ) extracellularly and neurofibrillary tangles (NFTs) formed by hyperphosphorylated tau protein intracellularly. Apart from these two features, insulin deficiency and insulin resistance...

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Bibliographic Details
Main Authors: Guanying You, Jinyi Yao, Qiong Liu, Nan Li
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/44/12/421