Unraveling patterns of site-to-site synonymous rates variation and associated gene properties of protein domains and families.

In protein-coding genes, synonymous mutations are often thought not to affect fitness and therefore are not subject to natural selection. Yet increasingly, cases of non-neutral evolution at certain synonymous sites were reported over the last decade. To evaluate the extent and the nature of site-spe...

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Bibliographic Details
Main Authors: Slavica Dimitrieva, Maria Anisimova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4045579?pdf=render