Strong interactions between highly dynamic lamina-associated domains and the nuclear envelope stabilize the 3D architecture of Drosophila interphase chromatin

Abstract Background Interactions among topologically associating domains (TADs), and between the nuclear envelope (NE) and lamina-associated domains (LADs) are expected to shape various aspects of three-dimensional (3D) chromatin structure and dynamics; however, relevant genome-wide experiments that...

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Bibliographic Details
Main Authors: Igor S. Tolokh, Nicholas Allen Kinney, Igor V. Sharakhov, Alexey V. Onufriev
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:https://doi.org/10.1186/s13072-023-00492-9