Prenatal Progestin Exposure-Mediated Oxytocin Suppression Contributes to Social Deficits in Mouse Offspring

Prenatal Progestin Exposure-Mediated Oxytocin Suppression Contributes to Social Deficits in Mouse Offspring

Epidemiological studies have shown that maternal hormone exposure is associated with autism spectrum disorders (ASD). The hormone oxytocin (OXT) is a central nervous neuropeptide that plays an important role in social behaviors as well as ASD etiology, although the detailed mechanism remains largely...

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Bibliographic Details
Main Authors: Saijun Huang, Jiaying Zeng, Ruoyu Sun, Hong Yu, Haimou Zhang, Xi Su, Paul Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
Subjects:
autism spectrum disorders
oxytocin
oxidative stress
progestin
social deficits
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.840398/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.840398/full

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