Global Hypertranscription in the Mouse Embryonic Germline

Primordial germ cells (PGCs) are vital for inheritance and evolution. Their transcriptional program has been extensively studied and is assumed to be well known. We report here a remarkable global upregulation of the transcriptome of mouse PGCs compared to somatic cells. Using cell-number-normalized...

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Bibliographic Details
Main Authors: Michelle Percharde, Priscilla Wong, Miguel Ramalho-Santos
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717306782