Microtubule destabilization with colchicine increases the work output of myocardial slices

Cardiac microtubules have recently been implicated in mechanical dysfunction during heart failure. However, systemic intolerance and non-cardiac effects of microtubule-depolymerizing compounds have made it challenging to determine the effect of microtubules on myocardial performance. Herein, we leve...

Full description

Bibliographic Details
Main Authors: Emmaleigh N. Hancock, Bradley M. Palmer, Matthew A. Caporizzo
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of Molecular and Cellular Cardiology Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772976124000060