Microtubule destabilization with colchicine increases the work output of myocardial slices
Cardiac microtubules have recently been implicated in mechanical dysfunction during heart failure. However, systemic intolerance and non-cardiac effects of microtubule-depolymerizing compounds have made it challenging to determine the effect of microtubules on myocardial performance. Herein, we leve...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-03-01
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Series: | Journal of Molecular and Cellular Cardiology Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772976124000060 |