(–)-Epicatechin Provides Neuroprotection in Sodium Iodate-Induced Retinal Degeneration

(–)-Epicatechin Provides Neuroprotection in Sodium Iodate-Induced Retinal Degeneration

Oxidative stress, mitochondrial impairment, and pathological amyloid beta (Aβ) deposition are involved in the pathogenesis of dry age-related macular degeneration (AMD). The natural flavonoid (–)-epicatechin (EC) is known to be an antioxidant and neuroprotective compound. Whether EC plays a therapeu...

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Bibliographic Details
Main Authors: Manjuan Peng, Xuezhi Zhou, Fei Yao, Haibo Li, Weitao Song, Siqi Xiong, Xiaobo Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Medicine
Subjects:
age-related macular degeneration
(–)-epicatechin
mitochondrial dynamics
mitochondrial quality control
TMEM97
amyloid beta
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.879901/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.879901/full

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