MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis

MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis

IntroductionPeriapical alveolar bone loss is the common consequence of apical periodontitis (AP) caused by persistent local inflammation around the apical area. Human stem cells from apical papilla (hSCAPs) play a crucial role in the restoration of bone lesions during AP. Studies have recently ident...

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Bibliographic Details
Main Authors: Jing Hu, Xia Huang, Liwen Zheng, Yuxin Zhang, Huan Zeng, Li Nie, Xiaoxiao Pang, Hongmei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
apical periodontitis
microRNA
miR-199a-5p
human stem cells from apical papilla (hSCAPs)
osteogenic differentiation
bone regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1149339/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1149339/full

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