Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection

Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection

Abstract C. difficile infection (CDI) is a worldwide healthcare problem with ~30% of cases failing primary therapy, placing a burden on healthcare systems and increasing patient morbidity. We have little understanding of why these therapies fail. Here, we use a clinically validated in vitro gut mode...

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Bibliographic Details
Main Authors: Charmaine Normington, Ines B. Moura, Jessica A. Bryant, Duncan J. Ewin, Emma V. Clark, Morgan J. Kettle, Hannah C. Harris, William Spittal, Georgina Davis, Matthew R. Henn, Christopher B. Ford, Mark H. Wilcox, Anthony M. Buckley
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-021-00184-w

Internet

https://doi.org/10.1038/s41522-021-00184-w

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