Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma.

Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma.

<h4>Introduction</h4>Surgical resection and systemic chemotherapy with temozolomide remain the mainstay for treatment of glioblastoma. However, many patients are not candidates for surgical resection given inaccessible tumor location or poor health status. Furthermore, despite being firs...

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Bibliographic Details
Main Authors: Matthew C Garrett, Timothy M O'Shea, Alexander L Wollenberg, Alexander M Bernstein, Derek Hung, Brittany Staarman, Horacio Soto, Timothy J Deming, Michael V Sofroniew, Harley I Kornblum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219632

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https://doi.org/10.1371/journal.pone.0219632

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