Improvement of islet transplantation by the fusion of islet cells with functional blood vessels

Improvement of islet transplantation by the fusion of islet cells with functional blood vessels

Abstract Pancreatic islet transplantation still represents a promising therapeutic strategy for curative treatment of type 1 diabetes mellitus. However, a limited number of organ donors and insufficient vascularization with islet engraftment failure restrict the successful transfer of this approach...

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Bibliographic Details
Main Authors: Lisa Nalbach, Leticia P Roma, Beate M Schmitt, Vivien Becker, Christina Körbel, Selina Wrublewsky, Mandy Pack, Thomas Später, Wolfgang Metzger, Maximilian M Menger, Florian S Frueh, Claudia Götz, Haopeng Lin, Jocelyn E Manning Fox, Patrick E MacDonald, Michael D Menger, Matthias W Laschke, Emmanuel Ampofo
Format: Article
Language:English
Published: Springer Nature 2020-11-01
Series:EMBO Molecular Medicine
Subjects:
diabetes
insulin
islet transplantation
microvascular fragments
vascularization
Online Access:https://doi.org/10.15252/emmm.202012616

Internet

https://doi.org/10.15252/emmm.202012616

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