Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats

Abstract Midlife hypertension is an important risk factor for cognitive impairment and dementia, including Alzheimer’s disease. We investigated the effects of long-term treatment with two classes of antihypertensive drugs to determine whether diverging mechanisms of blood pressure lowering impact th...

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Bibliographic Details
Main Authors: Daphne M. P. Naessens, Judith de Vos, Edo Richard, Micha M. M. Wilhelmus, Cornelis A. M. Jongenelen, Edwin R. Scholl, Nicole N. van der Wel, Johannes A. Heijst, Charlotte E. Teunissen, Gustav J. Strijkers, Bram F. Coolen, Ed VanBavel, Erik N. T. P. Bakker
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30515-0