Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats
Abstract Midlife hypertension is an important risk factor for cognitive impairment and dementia, including Alzheimer’s disease. We investigated the effects of long-term treatment with two classes of antihypertensive drugs to determine whether diverging mechanisms of blood pressure lowering impact th...
Main Authors: | Daphne M. P. Naessens, Judith de Vos, Edo Richard, Micha M. M. Wilhelmus, Cornelis A. M. Jongenelen, Edwin R. Scholl, Nicole N. van der Wel, Johannes A. Heijst, Charlotte E. Teunissen, Gustav J. Strijkers, Bram F. Coolen, Ed VanBavel, Erik N. T. P. Bakker |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-30515-0 |
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