A shear stress micromodel of urinary tract infection by the Escherichia coli producing Dr adhesin.

In this study, we established a dynamic micromodel of urinary tract infection to analyze the impact of UT-segment-specific urinary outflow on the persistence of E. coli colonization. We found that the adherence of Dr+ E. coli to bladder T24 transitional cells and type IV collagen is maximal at lowes...

Full description

Bibliographic Details
Main Authors: Beata Zalewska-Piątek, Marcin Olszewski, Tomasz Lipniacki, Sławomir Błoński, Miłosz Wieczór, Piotr Bruździak, Anna Skwarska, Bogdan Nowicki, Stella Nowicki, Rafał Piątek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008247