The Role of Intraperitoneal Intraoperative Chemotherapy with Paclitaxel in the Surgical Treatment of Peritoneal Carcinomatosis from Ovarian Cancer—Hyperthermia versus Normothermia: A Randomized Controlled Trial

Background: The treatment of ovarian carcinomatosis with cytoreductive surgery and HIPEC is still controversial. The effect and pharmacokinetics of the chemotherapeutics used (especially taxanes) are currently under consideration. Methods: A phase II, simple blind and randomized controlled trial (NT...

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Main Authors: Angela Casado-Adam, Lidia Rodriguez-Ortiz, Sebastian Rufian-Peña, Cristobal Muñoz-Casares, Teresa Caro-Cuenca, Rosa Ortega-Salas, Maria Auxiliadora Fernandez-Peralbo, Maria Dolores Luque-de-Castro, Juan M. Sanchez-Hidalgo, Cesar Hervas-Martinez, Antonio Romero-Ruiz, Javier Briceño, Álvaro Arjona-Sánchez
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/19/5785