Immunometabolism characteristics and a potential prognostic risk model associated with TP53 mutations in breast cancer

Immunometabolism characteristics and a potential prognostic risk model associated with TP53 mutations in breast cancer

TP53, a gene with high-frequency mutations, plays an important role in breast cancer (BC) development through metabolic regulation, but the relationship between TP53 mutation and metabolism in BC remains to be explored. Our study included 1,066 BC samples from The Cancer Genome Atlas (TCGA) database...

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Bibliographic Details
Main Authors: Mengping Jiang, Xiangyan Wu, Shengnan Bao, Xi Wang, Fei Qu, Qian Liu, Xiang Huang, Wei Li, Jinhai Tang, Yongmei Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
TP53
prognostic model
immune heterogeneity
metabolic heterogeneity
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.946468/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.946468/full

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