73565 Defining tp53 tumor suppressor functions in zebrafish embryonal rhabdomyosarcoma
ABSTRACT IMPACT: By assessing function of mutant (patient-specific) tp53 in zebrafish embryonal rhabdomyosarcoma will inform clinicians of the severity of mutant tp53 alleles. OBJECTIVES/GOALS: This study aims to define loss- and gain-of-function TP53 mutations by comparing effects in tp53-null and...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2021-03-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866121004544/type/journal_article |