Lower Absolute Lymphocyte Count Before Conditioning Predicts High Relapse Risk in Patients After Haploidentical Peripheral Blood Stem Cell Transplantation With Low Dose Anti-Thymocyte Globulin/Post-Transplant Cyclophosphamide for GvHD Prophylaxis

Lower Absolute Lymphocyte Count Before Conditioning Predicts High Relapse Risk in Patients After Haploidentical Peripheral Blood Stem Cell Transplantation With Low Dose Anti-Thymocyte Globulin/Post-Transplant Cyclophosphamide for GvHD Prophylaxis

Standard anti-thymocyte globulin (ATG) weight-based dosing often resulted in highly variable ATG exposure, which had profound effects on relapse and survival, especially in recipients with relatively low absolute lymphocyte count (ALC) before conditioning. Data regarding rabbit ATG pharmacokinetics...

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Bibliographic Details
Main Authors: Xiao Zhou, Yu Cai, Jun Yang, Yin Tong, Huiying Qiu, Chongmei Huang, Kun Zhou, Xiaowei Xu, Jiahua Niu, Xinxin Xia, Ying Zhang, Chang Shen, Yu Wei, Xianmin Song, Liping Wan
Format: Article
Language:English
Published: SAGE Publishing 2022-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897221079739

Internet

https://doi.org/10.1177/09636897221079739

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