The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis

The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis

Glioblastoma cells adapt to changes in glucose availability through metabolic plasticity allowing for cell survival and continued progression in low-glucose concentrations. However, the regulatory cytokine networks that govern the ability to survive in glucose-starved conditions are not fully define...

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Bibliographic Details
Main Authors: Sarah F. Stuart, Ayenachew Bezawork-Geleta, Zammam Areeb, Juliana Gomez, Vanessa Tsui, Ahmad Zulkifli, Lucia Paradiso, Jordan Jones, Hong P. T. Nguyen, Tracy L. Putoczki, Paul V. Licciardi, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
IL-11
glioblastoma
glutaminolysis
survival
invasion
Online Access:https://www.mdpi.com/1422-0067/24/4/3356

Internet

https://www.mdpi.com/1422-0067/24/4/3356

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