Large-scale genomic analysis of global Klebsiella pneumoniae plasmids reveals multiple simultaneous clusters of carbapenem-resistant hypervirulent strains

Abstract Background Klebsiella pneumoniae (Kp) Gram-negative bacteria cause nosocomial infections and rapidly acquire antimicrobial resistance (AMR), which makes it a global threat to human health. It also has a comparatively rare hypervirulent phenotype that can lead to severe disease in otherwise...

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Bibliographic Details
Main Authors: Anton Spadar, João Perdigão, Susana Campino, Taane G. Clark
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Genome Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13073-023-01153-y