Residue-based correlation between equilibrium and rate constants is an experimental formulation of the consistency principle for smooth structural changes of proteins

The consistency principle represents a physicochemical condition requisite for ideal protein folding. It assumes that any pair of amino acid residues in partially folded structures has an attractive short-range interaction only if the two residues are in contact within the native structure. The resi...

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Bibliographic Details
Main Authors: Daisuke Kohda, Seiichiro Hayashi, Daisuke Fujinami
Format: Article
Language:English
Published: The Biophysical Society of Japan 2023-12-01
Series:Biophysics and Physicobiology
Subjects:
Online Access:https://doi.org/10.2142/biophysico.bppb-v20.0046