PD-1/PD-L1 pathway: A double-edged sword in periodontitis

Periodontitis is a disease caused by infection and immunological imbalance, which often leads to the destruction of periodontal tissue. Programmed death protein 1 (PD-1) and its ligand: programmed death ligand 1 (PD-L1) are important “immune checkpoint” proteins that have a negative regulatory effec...

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Bibliographic Details
Main Authors: Xiaowei Liu, Lei Yang, Xuelian Tan
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223000033