High prevalence of lipopolysaccharide mutants and R2-pyocin susceptible variants in Pseudomonas aeruginosa populations sourced from cystic fibrosis lung infections

High prevalence of lipopolysaccharide mutants and R2-pyocin susceptible variants in Pseudomonas aeruginosa populations sourced from cystic fibrosis lung infections

ABSTRACT Chronic, highly antibiotic-resistant infections in cystic fibrosis (CF) lungs contribute to increasing morbidity and mortality. Pseudomonas aeruginosa, a common CF pathogen, exhibits resistance to multiple antibiotics, contributing to antimicrobial resistance (AMR). These bacterial populati...

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Bibliographic Details
Main Authors: Madeline Mei, Preston Pheng, Detriana Kurzeja-Edwards, Stephen P. Diggle
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
R-pyocin
bacteriocin
Pseudomonas aeruginosa
cystic fibrosis
lipopolysaccharide
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01773-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01773-23

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