C-terminus glycans with critical functional role in the maturation of secretory glycoproteins.

The N-glycans of membrane glycoproteins are mainly exposed to the extracellular space. Human tyrosinase is a transmembrane glycoprotein with six or seven bulky N-glycans exposed towards the lumen of subcellular organelles. The central active site region of human tyrosinase is modeled here within les...

Full description

Bibliographic Details
Main Authors: Daniela Cioaca, Simona Ghenea, Laurentiu N Spiridon, Marioara Marin, Andrei-Jose Petrescu, Stefana M Petrescu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3097235?pdf=render