Rising of intracellular NAD+ level and oppositely directed changes in CD38 expression in hippocampal cells in experimental Alzheimer’s disease

The aim of the study was to assess the level of NAD+ in the brain of mice treated with beta-amyloid (Aβ), as well as to determine the activity of ADP-ribosyl cyclase/CD38 and the number of CD38-immunopositive neurons, astrocytes and endothelial cells. Material and methods. The Alzheimer’s disease mo...

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Bibliographic Details
Main Authors: A. A. Semenova, Ya. V. Gorina, E. D. Khilazheva, E. V. Kharitonova, A. B. Salmina
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Siberian Branch Publishing House 2021-10-01
Series:Сибирский научный медицинский журнал
Subjects:
Online Access:https://sibmed.elpub.ru/jour/article/view/661